...

7% Hypertonic Saline Solution

4.9 Rating based on 9,750+ happy customers

Original price was: $79.00.Current price is: $39.97.

HURRY!
LIMITED SUPPLY | 50% OFF 🔥
Select Strength: Compare Strengths Here
3%
or
7%
Secure Transactions With TruNeb™
Free Shipping
(From Florida)
FDA
Approved
30 Day
Returns
24/7 Customer
Service
Medical
Grade

AS SEEN ON

Which Hypertonic Saline Strength Is Best for Me?

Choose the column that best reflects your needs

Best for

Use frequency

Concentration

3% Sodium Chloride (NaCl)

Congestion Relief

Best for consistent, long-term use in chronic respiratory conditions

Daily Maintenance

Ideal for regular use to manage symptoms and prevent mucus buildup in chronic lung disease

Lower Concentration

Suitable for sensitive people, children, and first-time users
Sodium Chloride - Saline Solution 3% - Inhalation Solution for Nebuliser – Reduce Mucus and Allergy

7% Sodium Chloride (NaCl)

Severe Congestion Relief ⬆

Best for rapid, intensive treatment of mucus in the lungs

Acute Exacerbations ⬆

Effective for treating flare-ups of respiratory conditions, providing quick relief

Higher Concentration ⬆

Recommended for people needing a more aggressive approach to airway clearance
7% Saline Solution for Nebulizer Machine | Saline Solution for Inhalation & Nasal Irrigation | High 7% Concentration l 5ml Unit Dose

Why 3% Hypertonic Saline?

Sodium Chloride - Saline Solution 3% - Inhalation Solution for Nebuliser – Reduce Mucus and Allergy

Why 7% Hypertonic Saline?

7% Saline Solution for Nebulizer Machine | Saline Solution for Inhalation & Nasal Irrigation |

Nebulizer Compatibility

(Works With All Nebulizers)

Jet Nebulizers Compatible Saline Solution
Ultrasonic Nebulizers Compatible Saline Solution
Hypertonic Saline for Nebulizer

Top Respiratory Conditions Our Customers Use Hypertonic Saline For

Always consult with your doctor before using hypertonic saline to treat any condition.

*Not medical advice

Bronchiectasis

Bronchiectasis patients use hypertonic saline to enhance mucociliary clearance, reduce exacerbations, and improve quality of life.
Saline Solution for Bronchiectasis Patient Inhalation & Nasal Irrigation

RSV

Hypertonic saline is often used as a treatment for infants and children with RSV/bronchiolitis. It helps reduce airway edema, improve mucus clearance, and alleviate respiratory distress.
3% Hypertonic Saline Solution | A Saline Solution For RSV Patient

Tracheostomy

Bronchiectasis patients use hypertonic saline to enhance mucociliary clearance, reduce exacerbations, and improve quality of life.
Hypertonic Saline Solution For Tracheostomy Relief
3% Hypertonic Saline Solution for Inhalation via Nebuliser - Helps Clear Airways and Congestion from Lungs

Chronic Obstructive Pulmonary Disease (COPD)

Hypertonic saline is used as an adjunctive therapy in COPD to facilitate mucus clearance, reduce hospitalizations, and improve lung function.
Hypertonic saline for CF patients to improve mucus clearance

Cystic Fibrosis

Hypertonic saline is a standard treatment for CF patients to improve mucus clearance, lung function, and reduce exacerbation frequency.
Inhalation Solution for Nebuliser – Reduce Mucus and Allergy - Nebulizer Saline Solution

Chronic Mucus

Excess mucus production can be an uncomfortable symptom to deal with on a day to day basis. Hypertonic saline can help manage extra mucus and make it easier to cough up.
TruNeb - A Trusted Solution For Portable Nebulizer

4.9 Rating based on 9,750+ happy customers

4.9 Rating based on 9,750+ happy customers

How to Use

Use Process - Open Nebulizer Saline Vial

Step 1: Open Vial

Twist off the top to open.

Pour your 5ml Nebulizer Saline Solution 7%/3%

Step 2: Pour Solution

Pour into the nebulizer cup.

Operate the nebulizer that you choose for your saline solution

Step 3: Nebulize

Operate the nebulizer.

Put the nebulizer saline vials to dustbin after use

Step 4: Dispose of Vial

Throw away the empty vial.

High 3% Concentration Saline Solution l 25 Vials 5ml Unit Dose
Hypertonic Saline, 7%, in box, TruNeb, Vials of Saline

What's in the box?

4.9 Rating based on 9,750+ happy customers

Why TruNeb™

Other Options

See What Saline Customers Are Saying

4.9
Rated 4.8 out of 5
From 480 Ratings
5
455
4
15
3
10
2
0
1
0

Reviews

Cara N

Cara N

Almost perfect, just pricey
Reviewed on April 2, 2026
I really like the product itself and the vials are very convenient, but I do think the price is a little high for what it is. Shipping took a bit longer than I hoped, so that was a small letdown too. The item did arrive in good condition and it has been easy to use with my nebulizer, so I’m still mostly happy with it. I just wish it was a little more affordable and the delivery a little faster. The product quality seems good, but those two things kept me from giving a higher rating.
Blake C

Blake C

Great regular item
Reviewed on March 23, 2026
This is a great regular item to keep around. It’s easy to use, easy to store, and the vials are the right size for my needs. I also like how fast it shipped, since that saved me a lot of waiting. Everything came packed well and looked clean when I opened it. It has worked nicely with my nebulizer and has been dependable so far. I’m pleased with the quality and the overall value.
Amber J

Amber J

Helpful and easy
Reviewed on March 14, 2026
This has been helpful and easy to use. I like the single-use vials because they keep everything simple and reduce cleanup. The order came quickly and the packaging was secure. The solution itself works well with my nebulizer and the strength was what I was looking for. It feels like a reliable product that was made with care. Overall I’m very happy with this purchase and would recommend it.
Zachary M

Zachary M

Good experience overall
Reviewed on March 6, 2026
I’ve had a good experience overall with this product. The vials are easy to use and store, and I like that they come pre-portioned. Shipping was fast and the package arrived safely. It has been compatible with my nebulizer and the solution has been consistent from vial to vial. There’s nothing complicated about it, which is actually a good thing in my opinion. I’d buy this again when I run low.
Yvonne D

Yvonne D

Very convenient format
Reviewed on February 27, 2026
This format is really convenient for everyday use. I like that each vial is ready to go, which saves time and helps keep everything tidy. The product arrived quickly and was packed nicely. It works well with my nebulizer and I haven’t had any issues at all. The quality feels good and the whole purchase was easy. It’s a practical item that does what I need without any extra hassle.
Xavier P

Xavier P

Smooth and easy
Reviewed on February 18, 2026
The whole experience was smooth and easy. Ordering took no time, the shipping was quick, and the box showed up in good condition. I appreciate the convenience of the single-use vials because they make things cleaner and simpler. The solution itself has been reliable with my nebulizer and the higher concentration was exactly what I wanted. It feels like a well put together product. I’m happy with it overall.
Wendy F

Wendy F

Great for simple use
Reviewed on February 10, 2026
If you want something simple, this is a good choice. The vials are easy to open and the amount is already set, so there’s no extra work involved. I like how neatly everything was packed when it arrived. Shipping was quick and the product looked clean and professional. It has worked with my nebulizer just fine and has been consistent every time. I’m glad I ordered it and would do so again.
Victor H

Victor H

Works well and ships fast
Reviewed on February 1, 2026
This shipped fast and worked well right away. I like the clean packaging and the easy-to-use vials. The pre-portioned setup is a big plus because it makes my routine less annoying and more consistent. It fits my nebulizer without any trouble and the quality seems solid. I’ve had a good experience from the first order and would feel comfortable buying it again. Very straightforward and dependable.
Tina G

Tina G

Satisfied with the purchase
Reviewed on January 22, 2026
I’m satisfied with this purchase overall. The box arrived quickly, the vials were in good shape, and the product felt well made. I really appreciate the single-use format because it keeps everything easier and more organized. It has worked fine with my nebulizer and I haven’t had any issues so far. The price felt fair for the amount included. It’s a simple product that does the job well.
Steven K

Steven K

Very convenient to keep on hand
Reviewed on January 13, 2026
I like having this on hand because it is so convenient. The vials are small, easy to store, and simple to use when I need them. The shipping was fast and the product came well packed. It’s nice not to worry about a larger container or extra cleanup. The solution itself has worked as expected in my nebulizer and feels consistent. This has been a good, practical addition to my supplies.
Cara N

Cara N

Almost perfect, just pricey
Reviewed on April 2, 2026
I really like the product itself and the vials are very convenient, but I do think the price is a little high for what it is. Shipping took a bit longer than I hoped, so that was a small letdown too. The item did arrive in good condition and it has been easy to use with my nebulizer, so I’m still mostly happy with it. I just wish it was a little more affordable and the delivery a little faster. The product quality seems good, but those two things kept me from giving a higher rating.
Blake C

Blake C

Great regular item
Reviewed on March 23, 2026
This is a great regular item to keep around. It’s easy to use, easy to store, and the vials are the right size for my needs. I also like how fast it shipped, since that saved me a lot of waiting. Everything came packed well and looked clean when I opened it. It has worked nicely with my nebulizer and has been dependable so far. I’m pleased with the quality and the overall value.
Amber J

Amber J

Helpful and easy
Reviewed on March 14, 2026
This has been helpful and easy to use. I like the single-use vials because they keep everything simple and reduce cleanup. The order came quickly and the packaging was secure. The solution itself works well with my nebulizer and the strength was what I was looking for. It feels like a reliable product that was made with care. Overall I’m very happy with this purchase and would recommend it.
Zachary M

Zachary M

Good experience overall
Reviewed on March 6, 2026
I’ve had a good experience overall with this product. The vials are easy to use and store, and I like that they come pre-portioned. Shipping was fast and the package arrived safely. It has been compatible with my nebulizer and the solution has been consistent from vial to vial. There’s nothing complicated about it, which is actually a good thing in my opinion. I’d buy this again when I run low.
Yvonne D

Yvonne D

Very convenient format
Reviewed on February 27, 2026
This format is really convenient for everyday use. I like that each vial is ready to go, which saves time and helps keep everything tidy. The product arrived quickly and was packed nicely. It works well with my nebulizer and I haven’t had any issues at all. The quality feels good and the whole purchase was easy. It’s a practical item that does what I need without any extra hassle.
Xavier P

Xavier P

Smooth and easy
Reviewed on February 18, 2026
The whole experience was smooth and easy. Ordering took no time, the shipping was quick, and the box showed up in good condition. I appreciate the convenience of the single-use vials because they make things cleaner and simpler. The solution itself has been reliable with my nebulizer and the higher concentration was exactly what I wanted. It feels like a well put together product. I’m happy with it overall.
Wendy F

Wendy F

Great for simple use
Reviewed on February 10, 2026
If you want something simple, this is a good choice. The vials are easy to open and the amount is already set, so there’s no extra work involved. I like how neatly everything was packed when it arrived. Shipping was quick and the product looked clean and professional. It has worked with my nebulizer just fine and has been consistent every time. I’m glad I ordered it and would do so again.
Victor H

Victor H

Works well and ships fast
Reviewed on February 1, 2026
This shipped fast and worked well right away. I like the clean packaging and the easy-to-use vials. The pre-portioned setup is a big plus because it makes my routine less annoying and more consistent. It fits my nebulizer without any trouble and the quality seems solid. I’ve had a good experience from the first order and would feel comfortable buying it again. Very straightforward and dependable.
Tina G

Tina G

Satisfied with the purchase
Reviewed on January 22, 2026
I’m satisfied with this purchase overall. The box arrived quickly, the vials were in good shape, and the product felt well made. I really appreciate the single-use format because it keeps everything easier and more organized. It has worked fine with my nebulizer and I haven’t had any issues so far. The price felt fair for the amount included. It’s a simple product that does the job well.
Steven K

Steven K

Very convenient to keep on hand
Reviewed on January 13, 2026
I like having this on hand because it is so convenient. The vials are small, easy to store, and simple to use when I need them. The shipping was fast and the product came well packed. It’s nice not to worry about a larger container or extra cleanup. The solution itself has worked as expected in my nebulizer and feels consistent. This has been a good, practical addition to my supplies.
Emily R

Emily R

Easy to use and convenient
Reviewed on May 14, 2025
I ordered this for my nebulizer setup and it has been really easy to work with. The single-use vials are super convenient and save me from measuring anything out. I also like that the packaging feels clean and organized, which makes the whole process less of a hassle. Shipping was fast and everything arrived in good shape. The price is a little higher than some other saline options, but for the higher strength and the convenience of the vials, I think it makes sense. Overall I’m happy with it and will probably order again when I run low.
Cara L

Cara L

Shipping delays, but excellent product
Reviewed on February 28, 2025
The delivery took longer than I expected, but the product itself is excellent. Definitely helps with my breathing and is easy to use with my nebulizer. Very pleased with the quality, just wish it had arrived sooner.
Fred T

Fred T

Quick and effective shipping
Reviewed on February 21, 2025
Although the product is great, the shipping could have been faster. It took longer than expected. However, the quality of the solution compensates for the wait.
Ethan J

Ethan J

A bit delayed but good
Reviewed on February 15, 2025
The product is solid, definitely helps with my breathing issues. However, the shipping was slightly delayed, but the product itself is reliable. Will order again despite the small hiccup.
Tony K

Tony K

Great results, but pricey
Reviewed on February 14, 2025
The results are great, and my breathing has improved, but I do find it a bit pricey compared to other options. Nevertheless, quality is amazing.
Diane L

Diane L

Good Product, Slow Shipping
Reviewed on January 21, 2025
The product itself works great, and I’ve noticed significant improvement in my congestion. However, the shipping took longer than expected, which was disappointing. Still, it’s a good product if you’re willing to wait.
Evelyn T

Evelyn T

Not bad, but a bit pricey
Reviewed on January 15, 2025
I like the product; it works well with my nebulizer. However, I find it a bit expensive compared to other options. Still, it does the job nicely.
Tom B

Tom B

Good but Shipping was Delayed
Reviewed on January 9, 2025
I like the solution, it helps a lot with my breathing problem. However, it took a week longer to arrive than I expected. I thought it would be here much quicker. The product is good but I just wish they had better shipping.
Martha N

Martha N

Good but took long to arrive
Reviewed on January 2, 2025
The product is effective and really helps with my sinusitis, but the delivery took longer than expected. Was hoping it would arrive faster as mentioned. Other than that, no complaints about the quality.
Henry J

Henry J

A bit pricey but worth it
Reviewed on December 30, 2024
I found it a tad expensive, but overall, it helps me a lot. The delivery was a bit delayed, but customer service was helpful. I would buy this again because it works really well.
Andrew W

Andrew W

Good solution, slow shipment
Reviewed on February 8, 2025
The product itself is great, helping with my severe congestion. But the delivery took longer than I’d hoped, even with the free shipping option. I would still recommend it, just maybe plan ahead.
Linda E

Linda E

Good but Pricey
Reviewed on January 10, 2025
The product works really well and is very effective, but I find it quite expensive. I think the customer service could be better and shipping took longer than expected. But overall, it’s a good product if you don’t mind these minor issues.
John D

John D

Not worth the price
Reviewed on January 2, 2025
The product is okay, but I expected more for the price. It’s just average.
John D

John D

Not worth the price
Reviewed on January 2, 2025
The product is okay, but I expected more for the price. It’s just average.
John D

John D

Not worth the price
Reviewed on January 2, 2025
The product is okay, but I expected more for the price. It’s just average.
Mark R

Mark R

Okay but Customer Service Was Lacking
Reviewed on January 1, 2025
I got the product and it works fine, but I had some questions about my order and it took ages for them to reply. For the price I paid, I think I expected a bit more from the customer service. It’s a good product, but I hope they improve this part.
John D

John D

Not worth the price
Reviewed on December 20, 2024
The product is okay, but I expected more for the price. It’s just average. The solution works well but it was quite expensive for my budget, and the delivery took longer than expected.
Patricia R

Patricia R

Good Product, Delayed Shipping
Reviewed on September 10, 2024
Really effective for my asthma, but shipping took a week instead of the promised 2–5 days. Still, I like the product itself and will probably purchase again if delivery time improves.
Susan K

Susan K

Good, but Delivery Was Late
Reviewed on November 22, 2023
The solution itself works great, really helps my sinus congestion. However, the delivery took longer than expected. Was suppose to arrive in 2-5 days, but it took 8 days. Would still recommend for the product’s effectiveness.
Deborah P

Deborah P

Effective but Pricey
Reviewed on January 15, 2023
The solution is quite effective for my sinus problems, but I do feel it is a bit too expensive. I wish it was more affordable. Nevertheless, it does the job right, and that’s what matters.

Frequently Asked Questions

TruNeb Team Photo

Need more help with your order?

We’re here for you 24/7. Give us a call at 866-981-3958

Hypertonic saline is a saltwater solution with a higher concentration of salt than normal saline or body fluids. It can be nebulized for inhalation to help clear mucus from the airways in various respiratory conditions like COPD or cystic fibrosis.

Hypertonic saline draws water from the tissues into the airways, thinning mucus and making it easier to cough up. This process improves mucociliary clearance, allowing patients to breathe more comfortably while reducing the risk of infection. 

Common side effects of hypertonic saline include cough, chest tightness, bronchospasm, and a temporary increase in sputum production. Most side effects are mild and resolve quickly after treatment. Always ask your doctor if it’s safe to use hypertonic saline with your specific condition and health history.

Yes, hypertonic saline can be used in combination with other inhaled medications, like bronchodilators or mucolytics. However, it’s essential to follow the proper sequence of administration and timing as directed by your healthcare provider. Medications like albuterol are generally taken after the hypertonic saline to relieve any airway irritation.

Our medical-grade hypertonic saline is produced in an FDA-approved lab.  

Hypertonic saline isn’t recommended for asthma unless your doctor specifically prescribes it and gives you the okay. It can be irritating for people with serious asthma.

Just open the sterile vial (make sure not to touch the tip so there’s no contamination), pour it into your nebulizer, and complete your breathing treatment like normal. If you’re using a mesh nebulizer, run a few mL of distilled water after the treatment to remove residue from the mesh.

Use of hypertonic saline with a nebulizer

Hypertonic saline should be stored at room temperature. Avoid extreme cold or extreme heat. Do not use if the vial has been opened or damaged. Do not save unused saline after the vial has been opened.

Shop by Category Find What You Need

Portable Nebulizer

tilt-nebulizer-hero
Saline Solution for Nebulizer Machine | Saline Solution for Inhalation & Nasal Irrigation | High 3% & 7% Concentration l 25 Vials 5ml Unit Dose

Nebulizer
Saline