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3% Hypertonic Saline Solution

4.9 Rating based on 979 + happy customers

Original price was: $79.00.Current price is: $39.97.

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Which Hypertonic Saline Strength Is Best for Me?

Choose the column that best reflects your needs

Best for

Use frequency

Concentration

3% Sodium Chloride (NaCl)

Congestion Relief

Best for consistent, long-term use in chronic respiratory conditions

Daily Maintenance

Ideal for regular use to manage symptoms and prevent mucus buildup in chronic lung disease

Lower Concentration

Suitable for sensitive people, children, and first-time users
Sodium Chloride - Saline Solution 3% - Inhalation Solution for Nebuliser – Reduce Mucus and Allergy

7% Sodium Chloride (NaCl)

Severe Congestion Relief ⬆

Best for rapid, intensive treatment of mucus in the lungs

Acute Exacerbations ⬆

Effective for treating flare-ups of respiratory conditions, providing quick relief

Higher Concentration ⬆

Recommended for people needing a more aggressive approach to airway clearance
7% Saline Solution for Nebulizer Machine | Saline Solution for Inhalation & Nasal Irrigation | High 7% Concentration l 5ml Unit Dose

Why 3% Hypertonic Saline?

Sodium Chloride - Saline Solution 3% - Inhalation Solution for Nebuliser – Reduce Mucus and Allergy

Why 7% Hypertonic Saline?

7% Saline Solution for Nebulizer Machine | Saline Solution for Inhalation & Nasal Irrigation |

Nebulizer Compatibility

(Works With All Nebulizers)

Jet Nebulizers Compatible Saline Solution
Ultrasonic Nebulizers Compatible Saline Solution
Hypertonic Saline for Nebulizer

Top Respiratory Conditions Our Customers Use Hypertonic Saline For

Always consult with your doctor before using hypertonic saline to treat any condition.

*Not medical advice

Bronchiectasis

Bronchiectasis patients use hypertonic saline to enhance mucociliary clearance, reduce exacerbations, and improve quality of life.
Saline Solution for Bronchiectasis Patient Inhalation & Nasal Irrigation

RSV

Hypertonic saline is often used as a treatment for infants and children with RSV/bronchiolitis. It helps reduce airway edema, improve mucus clearance, and alleviate respiratory distress.
3% Hypertonic Saline Solution | A Saline Solution For RSV Patient

Tracheostomy

Bronchiectasis patients use hypertonic saline to enhance mucociliary clearance, reduce exacerbations, and improve quality of life.
Hypertonic Saline Solution For Tracheostomy Relief
3% Hypertonic Saline Solution for Inhalation via Nebuliser - Helps Clear Airways and Congestion from Lungs

Chronic Obstructive Pulmonary Disease (COPD)

Hypertonic saline is used as an adjunctive therapy in COPD to facilitate mucus clearance, reduce hospitalizations, and improve lung function.
Hypertonic saline for CF patients to improve mucus clearance

Cystic Fibrosis

Hypertonic saline is a standard treatment for CF patients to improve mucus clearance, lung function, and reduce exacerbation frequency.
Inhalation Solution for Nebuliser – Reduce Mucus and Allergy - Nebulizer Saline Solution

Chronic Mucus

Excess mucus production can be an uncomfortable symptom to deal with on a day to day basis. Hypertonic saline can help manage extra mucus and make it easier to cough up.
TruNeb - A Trusted Solution For Portable Nebulizer

4.9 Rating based on 9,750+ happy customers

4.9 Rating based on 9,750+ happy customers

How to Use

Use Process - Open Nebulizer Saline Vial

Step 1: Open Vial

Twist off the top to open.

Pour your 5ml Nebulizer Saline Solution 7%/3%

Step 2: Pour Solution

Pour into the nebulizer cup.

Operate the nebulizer that you choose for your saline solution

Step 3: Nebulize

Operate the nebulizer.

Put the nebulizer saline vials to dustbin after use

Step 4: Dispose of Vial

Throw away the empty vial.

High 3% Concentration Saline Solution l 25 Vials 5ml Unit Dose
Hypertonic Saline, 7%, in box, TruNeb, Vials of Saline

What's in the box?

4.9 Rating based on 9,750+ happy customers

Why TruNeb™

Other Options

Our Reviews

TruNeb™ Score

4.9

Excellent . 979 ratings

4.9

From 979 Ratings

5
855
4
84
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34
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5
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Photos from customers

Reviews

Showing 1-10 of 979

Jason W

Jason W

Verified Buyer
1 day ago
Easy to store and use
The little vials are easy to keep organized in a cabinet, and I like that I can use one at a time. It makes my routine feel less complicated. I’ve had no issues with the product itself and the ordering process was smooth. Pretty much exactly what I hoped for.
Brian C

Brian C

Verified Buyer
4 days ago
Arrived fast and intact
My order showed up faster than I expected and everything was in good shape. The box was secure and the vials were easy to open. I appreciate products like this that keep things simple. It works with my nebulizer and has been easy to incorporate into my routine.
Nathan J

Nathan J

Verified Buyer
1 week ago
Fast delivery and good packaging
My order came quickly and everything was packed nicely. I like that the vials are pre-measured because it takes away all the extra steps. It has been a simple and useful product for my routine. No complaints from me at all so far.
Mia T

Mia T

Verified Buyer
3 weeks ago
Easy daily use
These little vials make everything so much easier. I like that they are already measured out, so there is no mess and no guessing. The size is perfect for keeping in my bag too. I have been using them with my nebulizer and the process feels smooth and simple every time.
Angela M

Angela M

Verified Buyer
3 weeks ago
Great for regular use
I use nebulizer treatments fairly often and this has been a really good option for me. The pre-measured vials help a lot because I do not have to pour or measure anything. It feels more organized and less wasteful. Price was fair for the convenience, in my opinion.
Rachel N

Rachel N

Verified Buyer
3 weeks ago
Helpful for keeping a routine
I like having these ready whenever I need them. It keeps my nebulizer routine less stressful because I don’t have to prepare anything extra. The vials are small, clean, and easy to store. Shipping was also smooth, which made the whole experience better.
Sophie L

Sophie L

Verified Buyer
4 weeks ago
Works well with my setup
I was a little unsure if it would work with my nebulizer, but it fit without any trouble. That was a big plus. The individual vials make it simple to use one at a time and keep the rest clean. Overall a very straightforward product and exactly what I wanted.
Justin H

Justin H

Verified Buyer
1 month ago
Simple product, good value
I was looking for something straightforward and this fit the bill. The packaging is handy and the portions are already set, which makes the whole process a lot easier. No issues with compatibility on my end. For the price, I think it’s a pretty good value overall.
Emily D

Emily D

Verified Buyer
1 month ago
Nice quality and easy to use
This has been a solid purchase. The vials are uniform, easy to handle, and don’t make a mess. I also like that it comes in a larger pack so I don’t need to reorder all the time. Everything feels well made and consistent, which matters to me.
Ethan A

Ethan A

Verified Buyer
1 month ago
Good size packaging
The 25 pack is a good amount for me because it lasts a while without taking up too much space. I like that each vial is the same size and already ready to use. It just makes everything easier. The quality has been consistent and the order process was simple.
Jason W

Jason W

Verified Buyer
1 day ago
Easy to store and use
The little vials are easy to keep organized in a cabinet, and I like that I can use one at a time. It makes my routine feel less complicated. I’ve had no issues with the product itself and the ordering process was smooth. Pretty much exactly what I hoped for.
Brian C

Brian C

Verified Buyer
4 days ago
Arrived fast and intact
My order showed up faster than I expected and everything was in good shape. The box was secure and the vials were easy to open. I appreciate products like this that keep things simple. It works with my nebulizer and has been easy to incorporate into my routine.
Nathan J

Nathan J

Verified Buyer
1 week ago
Fast delivery and good packaging
My order came quickly and everything was packed nicely. I like that the vials are pre-measured because it takes away all the extra steps. It has been a simple and useful product for my routine. No complaints from me at all so far.
Angela M

Angela M

Verified Buyer
3 weeks ago
Great for regular use
I use nebulizer treatments fairly often and this has been a really good option for me. The pre-measured vials help a lot because I do not have to pour or measure anything. It feels more organized and less wasteful. Price was fair for the convenience, in my opinion.
Rachel N

Rachel N

Verified Buyer
3 weeks ago
Helpful for keeping a routine
I like having these ready whenever I need them. It keeps my nebulizer routine less stressful because I don’t have to prepare anything extra. The vials are small, clean, and easy to store. Shipping was also smooth, which made the whole experience better.
Sophie L

Sophie L

Verified Buyer
4 weeks ago
Works well with my setup
I was a little unsure if it would work with my nebulizer, but it fit without any trouble. That was a big plus. The individual vials make it simple to use one at a time and keep the rest clean. Overall a very straightforward product and exactly what I wanted.
Justin H

Justin H

Verified Buyer
1 month ago
Simple product, good value
I was looking for something straightforward and this fit the bill. The packaging is handy and the portions are already set, which makes the whole process a lot easier. No issues with compatibility on my end. For the price, I think it’s a pretty good value overall.
Emily D

Emily D

Verified Buyer
1 month ago
Nice quality and easy to use
This has been a solid purchase. The vials are uniform, easy to handle, and don’t make a mess. I also like that it comes in a larger pack so I don’t need to reorder all the time. Everything feels well made and consistent, which matters to me.
Ethan A

Ethan A

Verified Buyer
1 month ago
Good size packaging
The 25 pack is a good amount for me because it lasts a while without taking up too much space. I like that each vial is the same size and already ready to use. It just makes everything easier. The quality has been consistent and the order process was simple.
Daniel R

Daniel R

Verified Buyer
1 month ago
Very convenient packaging
I ordered this mainly because I wanted something pre-portioned and easy to grab when needed. The 5ml vials are super convenient and the box was packed well. It arrived quickly, which I always appreciate. So far it has been a nice, no-fuss product to keep on hand.
Mia T

Mia T

Verified Buyer
3 weeks ago
Easy daily use
These little vials make everything so much easier. I like that they are already measured out, so there is no mess and no guessing. The size is perfect for keeping in my bag too. I have been using them with my nebulizer and the process feels smooth and simple every time.
Helen W

Helen W

Verified Buyer
10 months ago
Good product but pricey
I find the product very good, but it’s a bit on the pricey side. Nonetheless, I appreciate the quality and results.
Edward D

Edward D

Verified Buyer
1 year ago
Helps with Congestion
I have noticed a big improvement in congestion since I started using this saline solution. It’s easy to use and does a good job.
Joseph K

Joseph K

Verified Buyer
1 year ago
Does the job
This product does the job well. It has really helped me with my breathing. I particularly like that it comes in pre-measured vials, makes it easy to use.
David F

David F

Verified Buyer
1 year ago
Works well
I have been using this saline solution for my lung issues, and it helps a lot with clearing mucus. It’s gentle and I can use it several times a day without any problems.
Michael V

Michael V

Verified Buyer
1 year ago
Arrived Late but Worth It
The solution is fantastic, though it did take longer than expected to arrive. That aside, it works very well, and I’d order it again.
Nancy C

Nancy C

Verified Buyer
1 year ago
Very helpful
This product has been very helpful for my sinus problems. I use it regularly and have seen a big improvement. It’s easy to use and I like that it comes in pre-measured vials.
Betty K

Betty K

Verified Buyer
1 year ago
Asthma relief
I use this saline solution for my asthma and it really helps me manage my symptoms. It’s gentle and never irritates. I would recommend it to anyone with respiratory issues. The pre-measured vials are super helpful.
Jessica B

Jessica B

Verified Buyer
1 year ago
Little Expensive but Good
Great product, but it’s a little expensive. I love the individual vials, makes it all more manageable though.
Tommy H

Tommy H

Verified Buyer
1 year ago
Good but a Bit Pricey
The solution works great, and I have no complaints about its effectiveness. However, I do think it’s a bit overpriced. It would be nice if there were discounts available for regular customers.
Patricia R

Patricia R

Verified Buyer
1 year ago
A Bit Expensive
I like the product, it’s effective for my breathing issues, but the price is a tad high. I hope there will be some discounts or a loyalty program soon.
Ronald H

Ronald H

Verified Buyer
1 year ago
Delivery Could Be Better
I am happy with the product itself—it’s effective and easy to use. However, the delivery took longer than I would have liked. But overall, a good purchase.
Frank K

Frank K

Verified Buyer
1 year ago
Effective but Expensive
The product works well, but I believe it’s a little over-priced. However, it is of good quality and does what it says. Delivery time was longer than expected.
Susan M

Susan M

Verified Buyer
1 year ago
Effective but costly
Been using this for a while now and it really helps clear my sinuses. The cost is the only downside, too high for the amount you get. Delivered on time though.
Mary T

Mary T

Verified Buyer
1 year ago
Could be a bit cheaper
The product does work as intended and I can feel the difference when I use it. However, I feel like it’s a bit too expensive for what it is. I wish they had better discounts or a loyalty program. It’s hard on my pension, but I do need it for my breathing treatments.
Arthur M

Arthur M

Verified Buyer
1 year ago
Delivered Late
The saline solution is good and helps my condition, but the delivery was late and that was frustrating.
Dorothy G

Dorothy G

Verified Buyer
2 years ago
Not Bad, but Pricey
This saline solution is effective and gentle. I do like using it, but I think it’s a bit on the pricy side. Would love to see some discounts or offers.
Henry J

Henry J

Verified Buyer
2 years ago
A bit overpriced
While the solution works for my COPD, it’s a bit too pricey. I’d buy it again if there’s a sale or discount offer. Works well though.
Gerald P

Gerald P

Verified Buyer
2 years ago
A Little Pricey
This product works fine, but the price could be better. It does deliver what it promises, but I’ve seen cheaper ones out there.
Linda F

Linda F

Verified Buyer
2 years ago
Good but slow to arrive
The product is effective, but I had to wait longer than expected for delivery. I think shipping could be improved.
Anna B

Anna B

Verified Buyer
1 year ago
Overpriced but Effective
The product has helped my breathing issues a lot, but I believe it’s overpriced. Would be nice if it was more affordable. Still, it works well.
Edwin H

Edwin H

Verified Buyer
1 year ago
Works well, shipping slow
The product work great but it took too long to arrive. Overall good.
Linda A

Linda A

Verified Buyer
2 years ago
Good but late delivery
The product does what it says, helps with breathing and breaking down mucus. The delivery was late which was annoying because I needed it urgently. Otherwise, it’s a good product.
Steven K

Steven K

Verified Buyer
2 years ago
Mixed feelings
The product itself is great, no complaints there. The delivery time was really long though, almost a week late. For the price I was expecting a bit better service.
Charles B

Charles B

Verified Buyer
2 years ago
Too expensive
I think it’s too costly for what you get even though it works okay. I’d suggest waiting for a discount or looking for cheaper alternatives.
Elanor V

Elanor V

Verified Buyer
1 year ago
Works Well, Price Could Improve
Product itself is good, helps with my breathing a lot. But, the price is higher than what I expected. Would be better if it was more affordable.

Frequently Asked Questions

TruNeb Team Photo

Need more help with your order?

We’re here for you 24/7. Give us a call at 866-981-3958

Hypertonic saline is a saltwater solution with a higher concentration of salt than normal saline or body fluids. It can be nebulized for inhalation to help clear mucus from the airways in various respiratory conditions like COPD or cystic fibrosis.

Hypertonic saline draws water from the tissues into the airways, thinning mucus and making it easier to cough up. This process improves mucociliary clearance, allowing patients to breathe more comfortably while reducing the risk of infection. 

Common side effects of hypertonic saline include cough, chest tightness, bronchospasm, and a temporary increase in sputum production. Most side effects are mild and resolve quickly after treatment. Always ask your doctor if it’s safe to use hypertonic saline with your specific condition and health history.

Yes, hypertonic saline can be used in combination with other inhaled medications, like bronchodilators or mucolytics. However, it’s essential to follow the proper sequence of administration and timing as directed by your healthcare provider. Medications like albuterol are generally taken after the hypertonic saline to relieve any airway irritation.

Our medical-grade hypertonic saline is produced in an FDA-approved lab.  

Hypertonic saline isn’t recommended for asthma unless your doctor specifically prescribes it and gives you the okay. It can be irritating for people with serious asthma.

Just open the sterile vial (make sure not to touch the tip so there’s no contamination), pour it into your nebulizer, and complete your breathing treatment like normal. If you’re using a mesh nebulizer, run a few mL of distilled water after the treatment to remove residue from the mesh.

Use of hypertonic saline with a nebulizer

Hypertonic saline should be stored at room temperature. Avoid extreme cold or extreme heat. Do not use if the vial has been opened or damaged. Do not save unused saline after the vial has been opened.

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Saline Solution for Nebulizer Machine | Saline Solution for Inhalation & Nasal Irrigation | High 3% & 7% Concentration l 25 Vials 5ml Unit Dose

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